The Ivarsson lab focuses on short linear motifs (SLiM) based interactions. With our research we aim to contribute with novel insights into the human protein-protein interaction networks in health and diseases, and provide detailed information on the specificity determinants of the interactions. We also explore how pathogens such as viruses exploit motif based interactions to take over the host cell. Our research is interdisciplinary and combines biochemical and biophysical methods with bioinformatics and cell-based assays. Our core method is proteomic peptide phage display, which we have developed over the last ten years. The PhD student will investigate how kinases use SLiM-based interactions as a part of substrate recognition, and how these interactions are regulated and deregulated.